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May 23, 2009

Bio Risk Update

As I learn more about the bio risk I've been studying, I'm settling in for a long-term effort. There's one experiment nearing completion that initially looked extremely risky, but I've come to think it's probably within the bounds of acceptable risk. It seems that already-existing organisms are enough like the organism being created, so that there will (probably) be parasites waiting for it if it's accidentally released.

However, I remain unconvinced that the broader class of experiments is safe, in the sense of unlikely to create harm. And if harm does happen, I remain unconvinced that the worst-case plausible scenario is at all acceptable.

So I'll keep learning about the various issues involved - ecology, population dynamics, molecular biology, invasive species, bacteriology - and I'll keep talking with the relevant researchers about what I learn. Meanwhile, I'll be re-directing some of my focus back to CRN.

Chris Phoenix

CRN Home Page

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May 15, 2009

What I've Been Up To: Risk Analysis

Sorry I haven't been posting here more regularly. The biotech issue I've been working on has really claimed all my attention. I've been learning a lot about bacteria...

So far, conversations have mostly gone like this: I say to an expert, "What ____ is doing seems potentially very dangerous, because ___ could happen, or at least no one has shown me a reason it can't, and I've talked to several experts already."

I get one of three replies:
1) "I don't think that's worth worrying about, and I'm not inclined to look further."
2) "I don't think it will happen, because of _____." Then I look up _____ and find that it's factually incorrect.
3) "It seems like this is worth looking into further. You should talk to more experts."

Is it just me, or should I be getting more worried as I get more and more responses of type 2 and 3?

So far, I haven't managed to get any experts in the field to say "Yes, this is really worrisome, and I'll use my reputation to try to get the researchers to back off." Of course, this is a very hard thing for any scientist to say. There's a chasm to be crossed between "This might be a problem" and "This might be a problem I should act on, even if it means criticizing eminent fellow scientists." And the magnitude of the potential problem does not seem to make it easier to cross that chasm.

This has some similarities with molecular manufacturing, and some differences. One major difference is that molecular manufacturing is still in the future, while the potentially dangerous bio research is going on today.

A major similarity is that there appears to be a potential for self-replicating systems to be immensely powerful - more powerful than most specialists' intuitions - but that potential is only visible to generalists and systems thinkers. The experts don't easily see it, don't want to see it, and usually either dismiss it or treat it as someone else's theoretical problem.

For the past week or so, I've been in communication with the researcher who's actually doing the work I (and several other experts in various related fields) think is dangerous. As long as he's talking, I'm avoiding taking action that could start a grassroots movement against his work. Such a movement could be very powerful in the short run - and would probably create a lot more heat than light, causing future research along the same lines to be obscured and harder to regulate.

If any of you have experience with a case where a scientist was successfully convinced that their research was riskier than they thought - risky enough to substantially modify their plan and delay their work - then please let me know how that was accomplished. If no one has heard of such a thing happening... then what does that say about how the scientific community handles newly discovered risk?

(Yes, I know about Asilomar. That was one event, decades ago. How common are such things?)

Chris Phoenix

CRN Home Page

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April 20, 2009

Why I've Been Busy

You may have noticed that I haven't posted in a few days. I've been busy working on another potentially dangerous technology.

I've recently become aware of an instance of biotech research that appears to potentially be extremely dangerous. The researchers acknowledge some of the danger, but may be too confident in their safety measures.

I've been working for the past week or two to pull together a group of scientists and risk experts, to build an opinion on the risk and whether it's appropriate to ask for the work to be postponed. This has been taking a substantial amount of my time. But we may have only months to affect the course of this research, while we probably have several years until molecular manufacturing arrives.

At this point, it seems likely that "going through channels" will get better results than applying grassroots pressure. And it's still possible that the risk is less than I think, in which case it would be unfortunate to raise alarm toward a group doing valuable and relatively safe scientific work.

That's why I'm not being specific about what the research is: it's too early for mass action or publicity (and it may never be needed). If all goes well, and the level of scientific alarm either grows to be self-sustaining or shrinks due to a finding of low risk, I'll be able to re-focus on CRN in a few weeks.

Meanwhile, I'll keep posting here every few days. My next post will probably be on RepRap - just in the last few days, it's achieved an exciting new capability. Watch this space...

Chris Phoenix

CRN Home Page

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March 14, 2009

Don't Forget CRN's Thirty Studies

A couple of days ago, Todd Andersen suggested that we create a list of tech questions related to developing molecular manufacturing.

We already have a list of questions. The first sixteen of our Thirty Studies - especially #3 through #12 - relate to the development of molecular manufacturing capabilities by various pathways. The studies were published several years ago, but are still quite relevant.

New technical questions keep arriving - Todd contributed four, and others come in through our web feedback form - and I plan to answer them on this blog.

Chris Phoenix

CRN Home Page

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March 12, 2009

Modeling the future

Tom Craver has an interesting idea: a Wiki model of the future.

Such models have equations and parameters, and (for example) simulate what will happen to the economy in a year or two. The Club of Rome built such a model, and their model has been very influential.

So, is it possible to build an open-source model? One in which anyone can contribute a bit of insight or knowledge, and the system processes all the bits until it comes out with a useful set of projections about the future?

CRN has engaged in online collaborative projects before, including our groundbreaking scenario project. And a model of the future would certainly be useful to us.

Of course, it wouldn't be just one model. A useful system would run lots of projections using different variants of the model, and then aggregate the projections, looking for patterns in the relation between assumptions and outcomes. This would take a lot of computer power, and could be done on an @home type platform.

The information input into the scenario process would benefit from semi-automated Delphi-like feedback. Different versions of a piece of data would be rated according to how they matched opinions from other users, as well as what effect they had on the model.

Does anyone here know enough about mathematical modeling of the future to say whether this idea might be worth implementing?

Chris Phoenix

CRN Home Page

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March 11, 2009

Yes, I'm Back From Sabbatical

As of Monday, Mike Treder moved to IEET, and I'm back in the saddle at CRN. I plan to do several tech posts per week, interspersed with more newsy or talksy posts (of which this is one).

Future plans for CRN include a new look and feel for the website. And I'm working to set up something approximating online tech-focused panel discussions with other notables of molecular manufacturing. And the newsletter will start coming out regularly again, with science essays.

You readers who have stuck with CRN this long - it is, in a very real sense, your organization. I want to thank you for your continued attention. And if there are things you want to see in CRN, now's a very good time to suggest them.

Chris Phoenix

CRN Home Page

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January 07, 2009

6th Birthday for CRN

Birthday-cake-6

We've just passed the sixth anniversary of CRN's founding, back in late December 2002. Since then, we've come a long way and accomplished a great deal, although we still have far to go in getting enough people motivated to take the right kind of action.

The good news is that after six years, the work of the Center for Responsible Nanotechnology has had at least some impact in raising awareness of the transformative and disruptive potential of molecular manufacturing, and we seem to have quieted nearly all of the outright skeptics.

However, that's only the first level of our three step mission:

  1. Raise awareness of the benefits, the dangers, and the possibilities for responsible use of advanced nanotechnology.
  2. Expedite a thorough examination of the environmental, humanitarian, economic, military, political, social, medical, and ethical implications of molecular manufacturing.
  3. Assist in the creation and implementation of wise, comprehensive, and balanced plans for responsible worldwide use of this transformative technology.

More news coming soon about our plans to move forward in 2009...

Mike Treder

CRN Home Page

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June 14, 2008

Light Blogging Ahead

I'm leaving tomorrow afternoon for Jeddah, Saudi Arabia, with a short stopover in Cairo, Egypt. It's not clear how much online access I'll have during the next week, or how much time I'll have for blogging. But I'll try to give updates when I can and perhaps also post some photos.


Meantime, I'd like to address a comment posted yesterday by Dan S, in which he said: 

Should CRN be renamed as “Center for Responsible Climate Policy”? I noted that MNT-related post are heavily outnumbered by climate-change related posts. Over past few years CRN focus clearly shifted from advanced nano to climate and ecology problems. This trend is extremely disappointing since there are a lot of organizations concerned with climate change issues and only one “Center for Responsible Nanotechnology”…

I can understand why you'd feel that way, Dan, and you're not the only one. We've heard from others who expressed similar complaints or concerns. 

Perhaps it will help if I explain some of our internal thinking and discussions over the last several months and years.

When CRN was founded in December 2002, our intent was: a) to assist in establishing the technical feasibility of exponential general-purpose molecular manufacturing; b) to mount a convincing argument that it would be a disruptive, transformative technology; and c) to raise awareness of the potential imminence of its arrival -- it could be soon, and it might appear rather suddenly.

In the "CRN at Five Years Old" status report that we published in January, we related that it appears we have been mostly successful in achieving the first two points above: a) feasibility and b) disruption. We're proud of what we have accomplished there. 

But where we've been less successful is in garnering agreement about the imminence of the technology's likely arrival, and the consequent urgency for preparation. We think, however, that this may not be so much a failure on our part as a recognition that technical work toward achieving molecular manufacturing is not progressing as fast as we were originally concerned that it might. And since the purpose of CRN is not prediction, but preparation, we're quite happy to say that the initial part of our work is done, and the time for hitting hard on the imminence/urgency message is not yet here. This doesn't mean that we won't continue writing and talking about the technology and its implications, because we will.

However, as we sit back and look at this big picture, we can also see how vital it is to understand that technological change does not occur in a vacuum, nor is it immune to the social, political, and economic conditions within which it develops. That's why we think it's so important to project the impacts of evolving changes in societies, cultures, other emerging technologies, and major environmental trends. 

If, for example, global warming continues at its present alarming rate and causes greater and greater ecological catastrophes, eventually throwing the world economy totally out of whack -- well, that's something that could affect how soon and how safely molecular manufacturing is developed and deployed. Or, if China's unprecedented growth rate shifts the balance of power either economically or militarily too quickly and makes the geopolitical situation dangerously unstable, that's something that could have a big impact on where, when, and how nanofactory technology comes into being. This, by the way, is a good explanation for why we went to such trouble to prepare eight future scenarios about the potential development of advanced nanotechnology.

So, we don't think that paying attention to these issues is beyond the scope of our mission. In fact, we believe that if we ignored such preeminent factors, we'd not be doing justice to the purposes for which we were founded. 

May 27, 2008

Learning Lessons


  1. Nuclear War
  2. Global Warming  
  3. Anti-aging Research

What do you suppose they have in common?

Besides the fact that the first one, if it's all out, stands a good chance of eliminating worries about the second one (because the war could bring a nuclear winter) while also making interest in the third one essentially obsolete -- besides all that, what do these three items have in common?

This blog and, more generally, the Center for Responsible Nanotechnology are concerned with: a) raising awareness of the benefits, the dangers, and the possibilities for responsible use of advanced nanotechnology; b) expediting a thorough examination of the environmental, humanitarian, economic, military, political, social, medical, and ethical implications of molecular manufacturing; and c) assisting in the creation and implementation of wise, comprehensive, and balanced plans for responsible worldwide use of this transformative technology.

What you've just read is CRN's mission statement. Now consider that other organizations concerned with other issues might adopt a similar statement regarding nuclear war, global warming, or anti-aging research. (Obviously, it's hard to imagine any sane person calculating benefits from nuclear war, but you could easily substitute nuclear energy for that clause.) 

But what these three issue areas have in common is that CRN (and other groups like ours) can learn lessons from each of them about raising awareness, encouraging studies, and developing solutions.

So, who has done the best? Which one is struggling the most, and why?



NUCLEAR WAR (& ENERGY)

We're tempted to say that those who have worked hard to prevent nuclear war are the most successful of the lot. Until, that is, you remember that their efforts did not get going until after an initial catastrophe already had taken place. When just two bombs can cause some 200,000 deaths in a few months (about half in the first few seconds), that does have a tendency to concentrate interest and activity. Since then, attempts to contain proliferation and avert nuclear war have been markedly successful, when you consider that in more than half a century, only a handful of nations have gained nuclear capability.


So, should CRN look at this as a model for success? Or, because it took a deadly crisis to generate wide interest, should this example be ruled out? Can we afford to wait for the first nano-weapon shots to be fired, thereby gaining the impetus needed to accomplish a global agreement on responsible administration of molecular manufacturing? We don't think so.

Consider this trenchant analysis from NuclearRisk.org:

For 99.9% of our tenure on this planet, we could wait for direct evidence of our errors before correcting our actions. Sometimes the results were horrendous, as in the two World Wars and the environmental degradation due to hydraulic mining (now outlawed). As bad as those results were, our trial and error approach did not threaten our existence as a species. But during the last 0.1% of our existence our physical power has become so great that we can no longer wait for direct evidence that we are on the wrong path before changing our ways. Given that 99.9% of humanity's data says trial and error works, it is understandable – but horribly dangerous – that we have not yet recognized the obsolescence of that approach.

This warning is about the obscene danger of taking a "trial and error" approach to nuclear war, but we think it applies equally well to the equally severe threats posed by a nanotech arms race and an out of control war.



GLOBAL WARMING / CLIMATE CHANGE

Those of us who take seriously the results published last November by the Intergovernmental Panel on Climate Change (IPCC) are becoming increasingly worried about the signs of impending danger and the lack of corresponding action.

The IPCC's latest report [PDF] — signed off by 130 nations including the U.S. and China — slams the door on any argument for delay and makes clear we must under no circumstances listen to those who urge that we wait for a more convenient time to take the needed steps, however difficult they may be.

As the New York Times put it:

Members of the panel said their review of the data led them to conclude as a group and individually that reductions in greenhouse gasses had to start immediately to avert a global climate disaster that could leave island states submerged and abandoned, African crop yields decreased by 50 percent, and cause over a 5 percent decrease in global gross domestic product.

Concerns about global warming are nothing new. Since at least the 1980s, some world leaders and many scientists have warned that atmospheric effects from human activity would begin causing problems in the 21st century. What is unexpected is how quickly some of those effects seem to be occurring -- and are now strengthening -- showing that the old models were far too conservative in their predictions.

Why are we still dragging our feet? Instead of decreasing, carbon dioxide emissions are rapidly accelerating. Why hasn't more been done? Is it because the plans proposed are just too unpalatable to the public and politicians alike? Is it because the oil and gas and goal and automobile manufacturer lobbies are just too strong? Or is it because we haven't yet had a full-scale environmental disaster, a cataclysm equal to Hiroshima and Nagasaki that's directly traceable to global warming? Have scientists not yet made a strong enough case? It's hard to imagine how the evidence could become more conclusive without clearly being way beyond the point of no return.

So, unfortunately, this model also does not look like a good one for molecular manufacturing policy advocates to emulate. 

 

 

ANTI-AGING RESEARCH

They're making lots of news, getting coverage everywhere from "60 Minutes" to Popular Science to the Wall Street Journal. They've hosted large conferences and built a significant foundation with a large staff and millions of dollars in contributions. Still, though, the research touted by the main exponents is usually dismissed and sometimes ridiculed by mainstream gerontologists. That situation is changing, but slowly.

 

Hoping to hurry things along, a series of large cash prizes is on offer for researchers able to demonstrate that aging in mice can be delayed or reversed. In effect, they're looking for the opposite of a major catastrophe, instead trying to provoke the achievement of a scientific "miracle" that will turn the world in their direction.

Could such an effort succeed for nanofactory technology? Possibly, although no one yet has figured out how to set up and market a competition that gains as much interest, publicity, and practical results as the M-Prize. That doesn't mean it won't happen in the future, but it also doesn't mean that it will.

Besides, even if this approach did generate a lot of researchers spending a lot of money to build the first operational molecular fabricator, that alone would offer no guarantee that CRN could fulfill our mission statement. Remember, our aim is not just to hurry the technology along. It's mostly about understanding all the implications of a nanofactory-enabled world and being prepared for it so that we don't have to suffer through a disastrous learning experience.

March 23, 2008

Updating the Blogroll

We've recently done some housecleaning on our Blogroll (see the list in the panel to the right), and removed several blogs that were either dead or largely inactive.

If you have a favorite blog that's not listed and you think it covers subjects relevant to responsible nanotechnology, please let us know. No guarantee that we'll add it, of course, but we're always interested in seeing good blogs.

Mike Treder

CRN Home Page

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