Computers tend to get about ten times faster in about five years. In ten years, 100 times faster; in fifteen years, 1000 times faster. This is called Moore's Law, and it's been quite steady and predictable for several decades.
Recently, Nanorex simulated a 25,374 atom machine called a worm gear. The simulation took about 370 hours of computer time. We might expect that five years from now, this would take about 37 hours--still painfully slow.
But a new thing is happening: computer time is being sold on the Internet. Amazon.com is selling computer time by the hour for 10 cents apiece. I doubt that the price per hour will rise as time goes by; meanwhile, the hour will get more and more powerful. Five years from now, the full simulation will need 37 hours and cost only $3.70.
NanoHive already is designed for @home (distributed computing) type use, so I'd expect it to be portable to the Amazon "cloud" which is designed to provide standard computer resources. In that case, a user running large simulations would be able to buy 100 CPUs in parallel for the 22 minutes the simulation would take on a 100-CPU cluster. If the user bought 1000 CPUs in parallel--I'm guessing that Amazon's computer network would support this--they still would pay only $0.10 per CPU-hour, and the simulation would take a bit over two minutes.
There are two ways to look at this. One is that private users will now have inexpensive access to a supercomputer. The other way to look at it is that for just $10 per clock hour--affordable even to hobbyists--researchers can get a ten-year jump on Moore's Law.
The rapid advance of Moore's Law is one of the reasons why we expect molecular manufacturing to get rapidly easier to develop. Now, as soon as a bit of software infrastructure is put in place, the widespread availability of supercomputing will advance by ten years or more.